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Antigenic Specificity | HP1-gamma |
Clone | [5G10-F7-A12] |
Host Species | Mouse |
Reactive Species | mouse, human, monkey, hamster, rat |
Isotype | IgG1 |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunocytochemistry (ICC), Immunoprecipitation (IP), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody detects endogenous levels of HP1-gamma and does not cross-react with related proteins. Seems to be involved in transcriptional silencing in heterochromatin-like complexes. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. May contribute to the association of the heterochromatin with the inner nuclear membrane through its interaction with lamin B receptor (LBR). Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins. |
Immunogen | Immunogen Type: Recombinant Protein Immunogen Description: Purified recombinant human HP1-gamma protein fragments expressed in E Coli. |
Other Names | [CBX 3; CBX3; CBX3_HUMAN; Chromobox homolog 3 (HP1 gamma homolog, Drosophila); Chromobox homolog 3; Chromobox protein homolog 3; GAMMA; HECH; Heterochromatin like protein 1; Heterochromatin protein 1 homolog gamma; Heterochromatin protein HP1 gamma] |
Gene, Accession # | [HP1-gamma], Gene ID: 11335, NCBI: NP_009207.2, UniProt: Q13185 |
Catalog # | MBS9400428 |
Price | $200, $255 |
Order / More Info | HP1-gamma Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |