Edit |   |
---|---|
Antigenic Specificity | MYSM1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Western blot analysis of extracts of MDA-MB-231 cell line, using MYSM1 antibody. Metalloprotease that specifically deubiquitinates monoubiquitinated histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Preferentially deubiquitinates monoubiquitinated H2A in hyperacetylated nucleosomes. Deubiquitination of histone H2A leads to facilitate the phosphorylation and dissociation of histone H1 from the nucleosome. Acts as a coactivator by participating in the initiation and elongation steps of androgen receptor (AR)-induced gene activation. |
Immunogen | Immunogen: A synthetic peptide of human MYSM1 |
Other Names | [MYSM1, partial; MYSM1; MYSM1] |
Gene, Accession # | [MYSM1], NCBI: JAO93533.1 |
Catalog # | MBS4150244 |
Price | $385 |
Order / More Info | MYSM1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |