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Antigenic Specificity | PADI4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemisty (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: PADI4 antibody detects endogenous levels of total PADI4. Description: This gene is a member of a gene family which encodes enzymes responsible for the conversion of arginine residues to citrulline residues. This gene may play a role in granulocyte and macrophage development leading to inflammation and immune response.Function: Catalyzes the citrullination/deimination of arginine residues of proteins such as histones, thereby playing a key role in histone code and regulation of stem cell maintenance. Citrullinates histone H1 at 'Arg-54' (to form H1R54ci), histone H3 at 'Arg-2', 'Arg-8', 'Arg-17' and/or 'Arg-26' (to form H3R2ci, H3R8ci, H3R17ci, H3R26ci, respectively) and histone H4 at 'Arg-3' (to form H4R3ci). Acts as a key |
Immunogen | Immunogen: A synthesized peptide derived from human PADI4 Subcellular Location: Cytoplasm. Nucleus. Cytoplasmic Granule. Cytoplasmic granules of eosinophils and neutrophils. Tissue Specificity: Expressed in eosinophils and neutrophils, not expressed in peripheral monocytes or lymphocytes. Predicted Cross Reactivity: Rabbit Similarity: Rabbit (82%) |
Other Names | [EC 3.5.3.15; HL 60 PAD; HL-60 PAD; PAD 4; PAD; PADI 4; PADI 5; PADI H protein; Padi4; PADI4_HUMAN; PADI5; PDI 4; PDI 5; PDI4; PDI5; Peptidyl arginine deiminase type IV; Peptidyl arginine deiminase type V; Peptidylarginine deiminase IV; Protein arginine deiminase; Protein arginine deiminase type 4; Protein arginine deiminase type IV; Protein-arginine deiminase type IV; Protein-arginine deiminase type-4] |
Gene, Accession # | [PADI4], Gene ID: 23569, NCBI: NP_036519.2, UniProt: Q9UM07 |
Catalog # | MBS9607341 |
Price | $240, $280 |
Order / More Info | PADI4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |