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Antigenic Specificity | MAP3K9 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peroxidase (HRP) conjugate |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. Plays an important role in the cascades of cellular responses evoked by changes in the environment. Once activated, acts as an upstream activator of the MKK/JNK signal transduction cascade through the phosphorylation of MAP2K4/MKK4 and MAP2K7/MKK7 which in turn activate the JNKs. The MKK/JNK signaling pathway regulates stress response via activator protein-1 (JUN) and GATA4 transcription factors. Plays also a role in mitochondrial death signaling pathway, including the release cytochrome c, leading to apoptosis. |
Immunogen | Immunogen: Recombinant Human Mitogen-activated protein kinase kinase kinase 9 protein (864-1098AA) |
Other Names | [Mitogen-activated protein kinase kinase kinase 9; Mixed lineage kinase 1; MAP3K9; MLK1; PRKE1] |
Gene, Accession # | [MAP3K9], Gene ID: 4293, NCBI: NP_001271159.1, UniProt: P80192 |
Catalog # | MBS7104446 |
Price | $160, $235 |
Order / More Info | MAP3K9 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |