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Antigenic Specificity | GATA3 |
Clone | [1A10D1] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | ascites |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FC/FACS), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | GATA3: GATA binding protein 3. The genes for all 4 subunits of the T-cell antigen receptor (alpha, beta, gamma and delta) are controlled by distinct enhancers and their enhancer-binding proteins. Marine and Winoto (1991) identified a common TCR regulatory element by demonstrating binding of the enhancer-binding protein GATA3 to the enhancer elements of all 4 TCR genes. GATA3 had been shown in the chicken to be an enhancer-binding protein containing a zinc finger domain. GATA3 mRNA was demonstrated by Northern blot analysis in T cells but not in B cells, macrophages, or HeLa cell lines. GATA3 is abundantly expressed in the T-lymphocyte lineage and is thought to participate in T-cell receptor gene activation through binding to enhancers. Laba |
Immunogen | Immunogen: Purified recombinant fragment of GATA3 (aa175-388) expressed in E. Coli. |
Other Names | [HDR] |
Gene, Accession # | [GATA3], Gene ID: 2625, NCBI: NP_001002295.1, UniProt: P23771 |
Catalog # | MBS8538404 |
Price | $280 |
Order / More Info | GATA3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |