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Antigenic Specificity | Exportin-5 Picoband |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | Add 0.2ml of distilled water will yield a concentration of 500ug/ml. |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Exportin-5 (XPO5) is a protein that in humans is encoded by the XPO5 gene. The International Radiation Hybrid Mapping Consortium mapped the XPO5 gene to chromosome 6. This gene encodes a member of the karyopherin family that is required for the transport of small RNAs and double-stranded RNA-binding proteins from the nucleus to the cytoplasm. The encoded protein translocates cargo through the nuclear pore complex in a RanGTP-dependent process.Protein Function: Mediates the nuclear export of proteins bearing a double-stranded RNA binding domain (dsRBD) and double-stranded RNAs (cargos). XPO5 in the nucleus binds cooperatively to the RNA and to the GTPase Ran in its active GTP-bound form. Proteins containing dsRBDs can associ |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human Exportin-5 (2-43aa AMDQVNALCEQLVKAVTVMMDPNSTQRYRLEALKFCEEFKEK), different from the related mouse sequence by four amino acids. Subcellular Localization: Nucleus. Cytoplasm. Shuttles between the nucleus and the cytoplasm. Tissue Specificity: Expressed in heart, brain, placenta, lung, skeletal muscle, kidney and pancreas. |
Other Names | [Exportin-5; Exp5; Ran-binding protein 21; XPO5; KIAA1291; RANBP21] |
Gene, Accession # | [XPO5], Gene ID: 57510, NCBI: NP_065801.1, UniProt: Q9HAV4 |
Catalog # | MBS1750797 |
Price | $280 |
Order / More Info | Exportin-5 Picoband Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |