Exportin-5 Picoband Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityExportin-5 Picoband
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatimmunogen affinity purified
Size0.1 mg
ConcentrationAdd 0.2ml of distilled water will yield a concentration of 500ug/ml.
ApplicationsWestern Blot (WB)
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DescriptionDescription: Exportin-5 (XPO5) is a protein that in humans is encoded by the XPO5 gene. The International Radiation Hybrid Mapping Consortium mapped the XPO5 gene to chromosome 6. This gene encodes a member of the karyopherin family that is required for the transport of small RNAs and double-stranded RNA-binding proteins from the nucleus to the cytoplasm. The encoded protein translocates cargo through the nuclear pore complex in a RanGTP-dependent process.Protein Function: Mediates the nuclear export of proteins bearing a double-stranded RNA binding domain (dsRBD) and double-stranded RNAs (cargos). XPO5 in the nucleus binds cooperatively to the RNA and to the GTPase Ran in its active GTP-bound form. Proteins containing dsRBDs can associ
ImmunogenImmunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human Exportin-5 (2-43aa AMDQVNALCEQLVKAVTVMMDPNSTQRYRLEALKFCEEFKEK), different from the related mouse sequence by four amino acids. Subcellular Localization: Nucleus. Cytoplasm. Shuttles between the nucleus and the cytoplasm. Tissue Specificity: Expressed in heart, brain, placenta, lung, skeletal muscle, kidney and pancreas.
Other Names[Exportin-5; Exp5; Ran-binding protein 21; XPO5; KIAA1291; RANBP21]
Gene, Accession #[XPO5], Gene ID: 57510, NCBI: NP_065801.1, UniProt: Q9HAV4
Catalog #MBS1750797
Price$280
Order / More InfoExportin-5 Picoband Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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