CTCF Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | CTCF |
| Clone | polyclonal |
| Host Species | n/a |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Description: Rabbit IgG polyclonal antibody for Transcriptional repressor CTCF(CTCF) detection. Tested with WB, IHC-P in Human;Mouse;Rat. Background: Transcriptional repressor CTCF also known as 11-zinc finger protein or CCCTC-binding factor is a transcription factor that in humans is encoded by the CTCF gene. This gene is a member of the BORIS + CTCF gene family and encodes a transcriptional regulator protein with 11 highly conserved zinc finger (ZF) domains. And this nuclear protein is able to use different combinations of the ZF domains to bind different DNA target sequences and proteins. Depending upon the context of the site, the protein can bind a histone acetyltransferase (HAT)-containing complex and function as a transcriptional act |
| Immunogen | Immunogen: E Coli-derived human CTCF recombinant protein (Position: K521-R727). Human CTCF shares 94% and 93.1% amino acid (aa) sequence identity with mouse and rat CTCF, respectively. Ig Type: Rabbit IgG |
| Other Names | [Transcriptional repressor CTCF; 11 zinc finger protein; 11 zinc finger transcriptional repressor; 11-zinc finger protein; CCCTC binding factor (zinc finger protein); CCCTC binding factor; CCCTC-binding factor; Ctcf; CTCF_HUMAN; CTCFL paralog; Transcriptional repressor CTCF; CCCTC-binding factor (zinc finger protein)], [CTCF; CTCF; MRD21] |
| Gene, Accession # | [CTCF], Gene ID: 10664, NCBI: NP_001177951.1, UniProt: P49711 |
| Catalog # | MBS178015 |
| Price | $315 |
| Order / More Info | CTCF Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Chaumeil J, Skok JA (April 2012). The role of CTCF in regulating V(D)J recombination. Curr. Opin. Immunol. 24(2): 153-9. 2. Filippova GN, Fagerlie S, Klenova EM, Myers C, Dehner Y, Goodwin G, Neiman PE, Collins SJ, Lobanenkov VV (June 1996). An exceptionally conserved transcriptional repressor, CTCF, employs different combinations of zinc fingers to bind diverged promoter sequences of avian and mammalian c-myc oncogenes. Mol. Cell. Biol. 16 (6): 2802-13. 3. Phillips JE, Corces VG (June 2009).CTCF: master weaver of the genome.Cell 137 (7): 1194-211. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.858.633.0165
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