HP1 alpha Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHP1 alpha
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formataffinity purified
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP), Flow Cytometry (FC/FACS)
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DescriptionSpecificity: HP1 alpha Antibody detects endogenous levels of total HP1 alpha. Component of heterochromatin that recognizes and binds histone H3 tails methylated at ' Lys-9' (H3K9me), leading to epigenetic repression. In contrast, it is excluded from chromatin when ' Tyr-41' of histone H3 is phosphorylated (H3Y41ph). Can interact with lamin-B receptor (LBR). This interaction can contribute to the association of the heterochromatin with the inner nuclear membrane. Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins.
ImmunogenImmunogen: A synthesized peptide derived from human HP1 alpha
Other Names[CBX5; Antigen p25; Heterochromatin protein 1 homolog alpha; HP1 alpha]
Gene, Accession #[HP1 alpha], Gene ID: 23468, NCBI: NP_001120793.1, UniProt: P45973
Catalog #MBS4750232
Price$335
Order / More InfoHP1 alpha Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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