Edit |   |
Antigenic Specificity | GLI3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | amphibia, chicken, chimpanzee, dog, monkey, mouse, quail, rat |
Isotype | n/a |
Format | unconjugated |
Size | 0.05 mg |
Concentration | IgG concentration 0.5mg/ml |
Applications | ELISA (EIA), Immunohistology Paraffin*, Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This item recognizes the Human Zinc Finger protein 3 (GLI-3), also known as GLI-Kruppel family member 3, a 169.8kDa protein belonging to the GLI C2H2-type zinc finger protein of transcription factors.. . GLI-3 and the related GLI-2 proteins are the primary transcription factors that mediate Sonic hedgehog (Shh) signals in the mouse, GLI-2 being primarily a transcriptional activator while GLI-3 is a transcriptional repressor. GLI-3 plays a role in the development of the limbs and brain. It is expressed in a wide range of adult tissues including the colon, lung, spleen, testis and placenta.. . Defects in GLI3 are causative of a range of disease states including Pallister-Hall syndrome, type IV preaxial polydactyly, acrocallosal syndrome ( |
Immunogen | Immunogen: Synthetic peptide corresponding to amino acid sequence 41-57 of human Gli3 protein. Histology Positive Control Tissue: Human brain, glioblastoma Buffer Solution: Phosphate buffered saline Antiserum Preparation: Antiserum to human GLI3 was raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography. Target Species: Human |
Other Names | [transcriptional activator GLI3; Transcriptional activator GLI3; transcriptional activator GLI3; GLI-Kruppel family member GLI3; glioma-associated oncogene family zinc finger 3; oncogene GLI3; zinc finger protein GLI3; GLI family zinc finger 3; GLI3 form of 190 kDa; GLI3-190; GLI3 full length protein; GLI3FL], [GLI3; GLI3; PHS; ACLS; GCPS; PAPA; PAPB; PAP-A; PAPA1; PPDIV; GLI3FL; GLI3-190; GLI3-190; GLI3FL; GLI3-83] |
Gene, Accession # | [GLI3], Gene ID: 2737, NCBI: NP_000159.3, UniProt: P10071 |
Catalog # | MBS222908 |
Price | $550 |
Order / More Info | GLI3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |