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Antigenic Specificity | Human IGF1R |
Clone | monoclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | IgG |
Format | unconjugated |
Size | 0.06 mL, 0.12 mL, 0.2 mL |
Concentration | n/a |
Applications | Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cyometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The insulin-like growth factor-1 receptor (IGF1R) is a transmembrane tyrosine kinase involved in several biological processes including cell proliferation, differentiation, DNA repair, and cell survival. This a disulfide-linked heterotetrameric transmembrane protein consisting of two alpha and two beta subunits, and among which, the alpha subunit is extracellular while the beta subunit has an extracellular domain, a transmembrane domain and a cytoplasmic tyrosine kinase domain. IGF1R signalling pathway is activated in the mammalian nervous system from early developmental stages. Its major effect on developing neural cells is to promote their growth and survival. This pathway can integrate its action with signalling pathways of growth and mo |
Immunogen | Immunogen: Recombinant Human IGF1R/CD221 protein Buffer: 0.2 mum filtered solution in PBS with 5% trehalose |
Other Names | [IGF1R, partial; insulin like growth factor 1 receptor; insulin-like growth factor I receptor; insulin-like growth factor type 1 receptor] |
Gene, Accession # | [IGF1R ], Gene ID: 443515 |
Catalog # | MBS2543867 |
Price | $215, $330, $500 |
Order / More Info | Human IGF1R Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |