Caspase-10 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCaspase-10
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
FormatDEAE purified
Size0.1 mg
Concentrationn/a
ApplicationsELISA (EIA), Western Blot (WB)
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DescriptionSpecificity: Antibody only recognizes FLICE2 form of caspase-10. Caspase-10 Antibody: Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain (DD)- containing adapter molecules and members of the ICE/CED-3 protease family. A novel ICE/CED-3 protease was identified recently, designated FLICE2 and Mch4 and renamed as caspase-10. Caspase-10 has two death effector domains (DEDs) that bind to the DED in the adapter molecule FADD and recruits both TNFR1 and CD95 to form complexes with these receptors. Caspase-10 is therefore involved in the CD95 and TNFR1 induced apoptosis. Caspase-10 cleaves and activates caspase-3, -4, -6, -7, -8 and -9, which cau
ImmunogenImmunogen: Caspase-10 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human Caspase-10. Buffer: Caspase-10 Antibody is supplied in PBS containing 0.02% sodium azide.
Other Names[Caspase-10; MCH4; Caspase-10; Apoptotic protease Mch-4; CASP-10; caspase 10, apoptosis-related cysteine peptidase], [CASP10; CASP10; MCH4; ALPS2; FLICE2; MCH4; CASP-10; FLICE2]
Gene, Accession #[CASP10], Gene ID: 843, NCBI: AAD28402, UniProt: Q92851
Catalog #MBS150630
Price$375
Order / More InfoCaspase-10 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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