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Antigenic Specificity | Caspase-10 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | DEAE purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Antibody only recognizes FLICE2 form of caspase-10. Caspase-10 Antibody: Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain (DD)- containing adapter molecules and members of the ICE/CED-3 protease family. A novel ICE/CED-3 protease was identified recently, designated FLICE2 and Mch4 and renamed as caspase-10. Caspase-10 has two death effector domains (DEDs) that bind to the DED in the adapter molecule FADD and recruits both TNFR1 and CD95 to form complexes with these receptors. Caspase-10 is therefore involved in the CD95 and TNFR1 induced apoptosis. Caspase-10 cleaves and activates caspase-3, -4, -6, -7, -8 and -9, which cau |
Immunogen | Immunogen: Caspase-10 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human Caspase-10. Buffer: Caspase-10 Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [Caspase-10; MCH4; Caspase-10; Apoptotic protease Mch-4; CASP-10; caspase 10, apoptosis-related cysteine peptidase], [CASP10; CASP10; MCH4; ALPS2; FLICE2; MCH4; CASP-10; FLICE2] |
Gene, Accession # | [CASP10], Gene ID: 843, NCBI: AAD28402, UniProt: Q92851 |
Catalog # | MBS150630 |
Price | $375 |
Order / More Info | Caspase-10 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |