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Antigenic Specificity | ITGB3BP |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Western blot analysis of extracts of various cell lines, using ITGB3BP antibody. This gene encodes a transcriptional coregulator that binds to and enhances the activity of members of the nuclear receptor families, thyroid hormone receptors and retinoid X receptors. This protein also acts as a corepressor of NF-kappaB-dependent signaling. This protein induces apoptosis in breast cancer cells through a caspase 2-mediated signaling pathway. This protein is also a component of the centromere-specific histone H3 variant nucleosome associated complex (CENP-NAC) and may be involved in mitotic progression by recruiting the histone H3 variant CENP-A to the centromere. Alternate splicing results in multiple transcript variants. |
Immunogen | Immunogen: Recombinant protein of human ITGB3BP |
Other Names | [ITGB3BP protein; Centromere protein R; centromere protein R; integrin subunit beta 3 binding protein; Beta-3-endonexin; Integrin beta-3-binding protein; Nuclear receptor-interacting factor 3] |
Gene, Accession # | [ITGB3BP], Gene ID: 23421, NCBI: AAH14385.1 |
Catalog # | MBS4150645 |
Price | $385 |
Order / More Info | ITGB3BP Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |