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Antigenic Specificity | Histone H1 (Nuclear Marker) |
Clone | [r1415-1] |
Host Species | Mouse |
Reactive Species | human, mouse, rat. |
Isotype | IgG1 |
Format | unconjugated |
Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC) Formalin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Eukaryotic histones are basic and water-soluble nuclear proteins that form hetero-octameric nucleosome particles by wrapping 146 base pairs of DNA in a left-handed super-helical turn sequentially to form chromosomal fiber. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form the octamer; formed of two H2A-H2B dimers and two H3-H4 dimers, forming two nearly symmetrical halves by tertiary structure. Over 80% of nucleosomes contain the linker Histone H1, derived from an intronless gene that interacts with linker DNA between nucleosomes and mediates compaction into higher order chromatin. Histones are subject to posttranslational modification by enzymes primarily on their N-terminal tails, but also in their g |
Immunogen | Immunogen: Nuclei of human leukemia biopsy cells Cellular Localization: Nuclear |
Other Names | [H1(0); H1.1; H1.2; H1.3; H1.4; H1.5; H10; H1A; H1F0; H1F1; H1F2; H1F3; H1F4; H1F5; H1FNT; H1FOO; H1FT; H1FV; H1FX; H1t; H1T2; H1X; HANP1; His1; HisC; HIST1; HIST1H1A; HIST1H1B; HIST1H1C; HIST1H1D; HIST1H1E; HIST1H1T; Oocyte-specific histone H1; Testicular H1 histone] |
Gene, Accession # | [H1], Gene ID: 2670, NCBI: NP_001124491.1, UniProt: P14136 |
Catalog # | MBS4380011 |
Price | $190, $340, $340 |
Order / More Info | Histone H1 (Nuclear Marker) Antibody from MYBIOSOURCE INC. |
Product Specific References | Debus E, et. al. 1983, Differentiation, 25(2):193-203. Van Muijen GN et. al. 1987, Lab Invest, 57:359-369. Herpers MJ et. Al. 1986, Acta Neuropathol, 70:333-339. |