Edit |   |
---|---|
Antigenic Specificity | FAK |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | Protein A purified |
Size | 0.1 mg |
Concentration | 500 ug/ml |
Applications | Immunofluorescence (IF), Immunoprecipitation (IP), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Focal adhesion kinase was identified as a 125 kDa substrate for the intrinsic protein tyrosine kinase activity of Src encoded pp60. The deduced amino acid sequence of FAK p125 has shown it to be a cytoplasmic protein tyrosine kinase whose sequence and structural organization are unique as compared to other proteins described to date. Localization of p125 by immunofluorescence suggests that it is primarily found in cellular focal adhesions leading to its designation as focal adhesion kinase (FAK). FAK is concentrated at the basal edge of only those basal keratinocytes that are actively migrating and rapidly proliferating in repairing burn wounds and is activated and localized to the focal adhesions of spreading keratinocytes in culture. Thus |
Immunogen | Immunogen: FAK antibody was raised in Rabbit using recombinant human FAK as the immunogen. |
Other Names | [Rabbit FAK; FAK; FAK; Focal adhesion kinase] |
Gene, Accession # | [FAK] |
Catalog # | MBS5309100 |
Price | $705 |
Order / More Info | FAK Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |