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Antigenic Specificity | LATS1/2 (Phospho-Thr1079/1041) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody detects endogenous levels of LATS1/2 when Phospho occurs at Thr1079/1041. LATS1 (Large Tumor Suppressor Kinase 1) is a Protein Coding gene. Diseases associated with LATS1 include Tetraploidy and Soft Tissue Sarcoma. Among its related pathways are DNA Damage and Mesodermal Commitment Pathway. The protein encoded by LATS1 is a putative serine/threonine kinase that localizes to the mitotic apparatus and complexes with cell cycle controller CDC2 kinase in early mitosis. The N-terminal region of the protein binds CDC2 to form a complex showing reduced H1 histone kinase activity, indicating a role as a negative regulator of CDC2/cyclin A. In addition, the C-terminal kinase domain binds to its own N-terminal region, suggesting potent |
Immunogen | Immunogen: Synthesized peptide derived from part region of human LATS1/2 (Phospho-Thr1079/1041) Antibody protein |
Other Names | [Rabbit LATS1/2 (Phospho-Thr1079/1041); Serine/threonine-protein kinase LATS1; Large tumor suppressor homolog 1; WARTS protein kinase; h-warts] |
Gene, Accession # | [LATS1/2], Gene ID: 9113, NCBI: NM_004690.3, UniProt: O95835 |
Catalog # | MBS9709655 |
Price | $130, $220, $325 |
Order / More Info | LATS1/2 (Phospho-Thr1079/1041) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |