Human PYCARD / ASC Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Human PYCARD / ASC |
| Clone | polyclonal |
| Host Species | Goat |
| Reactive Species | Gibbon, gorilla, human. predicted reactivity: monkey (at least 90% immunogen sequence identity) |
| Isotype | n/a |
| Format | immunoaffinity purified |
| Size | 0.05 mg |
| Concentration | 0.5 mg/ml |
| Applications | Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Human PYCARD. This antibody is expected to recognise all reported Human isoforms according to NP_037390.2 and NP_660183.1. Apoptosis is regulated by death domain (DD) and/or caspase recruitment domain (CARD) containing molecules and a caspase family of proteases. CARD containing cell death regulators include RAIDD, RICK, BCL10, Apaf-1, ARC, caspase-9, and caspase-2. A novel CARD domain containing protein was recently identified in human and mouse and designated ASC and TMS1. Ectopic expression of ASC/TMS1 induced apoptosis through activation of caspase-9 and inhibited the survival of human breast cancer cells. |
| Immunogen | Immunogen Description: Synthetic peptide C-RESQSYLVEDLERS from the C-terminus of human PYCARD (NP_037390.2; NP_660183.1). Percent identity by BLAST analysis: Human, Gorilla, Gibbon (100%); Monkey (93%). |
| Other Names | [PYCARD / ASC (C-Terminus) IHC-plus; PYCARD; CARD5; HASC; ASC; TMS; TMS-1; PYD and CARD domain containing; TMS1; Human PYCARD; ASC], [ASC] |
| Gene, Accession # | [PYCARD], Gene ID: 29108, NCBI: NP_037390.2, UniProt: Q9ULZ3 |
| Catalog # | MBS247951 |
| Price | $530 |
| Order / More Info | Human PYCARD / ASC Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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