ASF1B Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityASF1B
Clone[AT1D4]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG2b, kappa
FormatProtein A purified
Size0.1 mL
Concentration1 mg/ml
ApplicationsELISA (EIA), Western Blot (WB)
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DescriptionASF1B is a member of the H3/H4 family of histone chaperone proteins and is similar to the anti-silencing function-1 gene in yeast. The encoded protein is the substrate of the tousled-like kinase family of cell cycle-regulated kinases, and may play a key role in modulating the nucleosome structure of chromatin by ensuring a constant supply of histones at sites of nucleosome assembly. Delivering histone H3/H4 dimers to CAF-1 or HIRA histone deposition complexes to facilitate replication-coupled and replication-independent nucleosome assembly on DNA. Both ASF1A and ASF1B are phosphorylated in S phase by the Tousled-like kinases TLK1 and TLK2, and are dephosphorylated when TLK1 and TLK2 are inactivated by Chk1 kinase in response to replicative
ImmunogenImmunogen: ASF1B antibody was raised in mouse using recombinant human ASF1B (1-202aa) purified from E Coli as the immunogen
Other Names[Mouse ASF1B; ASF1B; ASF1B; ASF1 silencing function 1 homolog B (S.cerevisiae); CIA-II]
Gene, Accession #[ASF1B], NCBI: CAG33516.1, UniProt: Q9NVP2
Catalog #MBS5310706
Price$375
Order / More InfoASF1B Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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