DOCK3 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityDOCK3
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatperoxidase (HRP) conjugate
Size0.05 mg, 0.1 mg
Concentrationn/a
ApplicationsELISA (EIA)
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DescriptionPotential guanine nucleotide exchange factor (GEF). GEF proteins activate some small GTPases by exchanging bound GDP for free GTP. Its interaction with presenilin proteins as well as its ability to stimulate Tau/MAPT phosphorylation suggest that it may be involved in Alzheimer disease. Ectopic expression in nerve cells decreases the secretion of beta-amyloid APBA1 protein and lowers the rate of cell-substratum adhesion, suggesting that it may affect the function of some small GTPase involved in the regulation of actin cytoskeleton or cell adhesion receptors (By similarity).
ImmunogenImmunogen: Recombinant human Dedicator of cytokinesis protein 3 protein
Other Names[Dedicator of cytokinesis protein 3; Modifier of cell adhesion; Presenilin-binding protein; PBP; DOCK3; KIAA0299; MOCA]
Gene, Accession #[DOCK3], Gene ID: 1795, NCBI: NP_004938.1, UniProt: Q8IZD9
Catalog #MBS7043634
Price$160, $235
Order / More InfoDOCK3 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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