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Antigenic Specificity | DOCK3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peroxidase (HRP) conjugate |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Potential guanine nucleotide exchange factor (GEF). GEF proteins activate some small GTPases by exchanging bound GDP for free GTP. Its interaction with presenilin proteins as well as its ability to stimulate Tau/MAPT phosphorylation suggest that it may be involved in Alzheimer disease. Ectopic expression in nerve cells decreases the secretion of beta-amyloid APBA1 protein and lowers the rate of cell-substratum adhesion, suggesting that it may affect the function of some small GTPase involved in the regulation of actin cytoskeleton or cell adhesion receptors (By similarity). |
Immunogen | Immunogen: Recombinant human Dedicator of cytokinesis protein 3 protein |
Other Names | [Dedicator of cytokinesis protein 3; Modifier of cell adhesion; Presenilin-binding protein; PBP; DOCK3; KIAA0299; MOCA] |
Gene, Accession # | [DOCK3], Gene ID: 1795, NCBI: NP_004938.1, UniProt: Q8IZD9 |
Catalog # | MBS7043634 |
Price | $160, $235 |
Order / More Info | DOCK3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |