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Antigenic Specificity | TXNIP - C-terminal region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | cow, dog, guinea pig, human, mouse, rabbit, rat, sheep |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This is a rabbit polyclonal antibody against TXNIP. It was validated on Western Blot using a cell lysate as a positive control.Target Description: TXNIP may act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. It interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. It functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest. It is required for the maturation of natural killer cells. |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human TXNIP |
Other Names | [thioredoxin-interacting protein isoform 1; Thioredoxin-interacting protein; thioredoxin-interacting protein; thioredoxin interacting protein; Thioredoxin-binding protein 2; Vitamin D3 up-regulated protein 1] |
Gene, Accession # | [TXNIP], Gene ID: 10628, NCBI: NP_006463, UniProt: Q9H3M7 |
Catalog # | MBS3210655 |
Price | $365 |
Order / More Info | TXNIP - C-terminal region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |