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Antigenic Specificity | DDIT3 (C-term A135), 120-149 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse (predicted reactivity: bovine, hamster) |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.42 |
Applications | Western Blot (WB), ELISA (EIA), Flow Cytometry (FC/FACS), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This DDIT3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 120-149 amino acids from the C-terminal region of human DDIT3. This gene encodes a member of the CCAAT/enhancer-bindingprotein (C/EBP) family of transcription factors. The proteinfunctions as a dominant-negative inhibitor by forming heterodimerswith other C/EBP members, such as C/EBP and LAP (liver activatorprotein), and preventing their DNA binding activity. The protein isimplicated in adipogenesis and erythropoiesis, is activated byendoplasmic reticulum stress, and promotes apoptosis. Fusion ofthis gene and FUS on chromosome 16 or EWSR1 on chromosome 22induced by translocation generates chimeric proteins |
Immunogen | n/a |
Other Names | [DNA damage-inducible transcript 3 protein; DDIT-3; C/EBP zeta; C/EBP-homologous protein; CHOP; C/EBP-homologous protein 10; CHOP-10; CCAAT/enhancer-binding protein homologous protein; Growth arrest and DNA damage-inducible protein GADD153; DDIT3; CHOP; CHOP10; GADD153] |
Gene, Accession # | [DDIT3], Gene ID: 1649, NCBI: NP_001181982.1, UniProt: P35638 |
Catalog # | MBS9209135 |
Price | $165, $370 |
Order / More Info | DDIT3 (C-term A135), 120-149 Antibody from MYBIOSOURCE INC. |
Product Specific References | Park, S.H., et al. J. Immunol. 185(9):5522-5530(2010) Goodall, J.C., et al. Proc. Natl. Acad. Sci. U.S.A. 107(41):17698-17703(2010) Zhang, H.M., et al. J. Virol. 84(17):8446-8459(2010) Cazanave, S.C., et al. Am. J. Physiol. Gastrointest. Liver Physiol. 299 (1), G236-G243 (2010) : Wang, Y.L., et al. J. Exp. Clin. Cancer Res. 29, 54 (2010) : |