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Antigenic Specificity | PLA2G6 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: 85 kDa calcium-independent phospholipase A2 is an enzyme that in humans is encoded by the PLA2G6 gene. The protein encoded by this gene is an A2 phospholipase, a class of enzyme that catalyzes the release of fatty acids from phospholipids. The encoded protein may play a role in phospholipid remodelling, arachidonic acid release, leukotriene and prostaglandin synthesis, fas-mediated apoptosis, and transmembrane ion flux in glucose-stimulated B-cells. Several transcript variants encoding multiple isoforms have been described, but the full-length nature of only three of them have been determined to date. Protein Function: Catalyzes the release of fatty acids from phospholipids. It has been implicated in normal phospholipid rem |
Immunogen | Immunogen: E Coli-derived human PLA2G6 recombinant protein (Position: W715-L802). Subcellular Localization: Isoform LH-iPLA2: Membrane; Recruited to the membrane-enriched pseudopod upon MCP1/CCL2 stimulation in monocytes. Tissue Specificity: Four different transcripts were found to be expressed in a distinct tissue distribution. |
Other Names | [85/88 kDa calcium-independent phospholipase A2; CaI-PLA2; Group VI phospholipase A2; GVI PLA2; Intracellular membrane-associated calcium-independent phospholipase A2 beta; iPLA2-beta; Patatin-like phospholipase domain-containing protein 9; PNPLA9; PLA2G6; PLPLA9] |
Gene, Accession # | [PLA2G6], Gene ID: 8398, NCBI: NP_001004426.1, UniProt: O60733 |
Catalog # | MBS1750686 |
Price | $280 |
Order / More Info | PLA2G6 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |