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Antigenic Specificity | CALR |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | ELISA (EIA), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This CALR Antibody is generated from rabbits immunized with a recombinant protein of human CALR. Calreticulin is a multifunctional protein that acts as amajor Ca(2+)-binding (storage) protein in the lumen of theendoplasmic reticulum. It is also found in the nucleus, suggestingthat it may have a role in transcription regulation. Calreticulinbinds to the synthetic peptide KLGFFKR, which is almost identicalto an amino acid sequence in the DNA-binding domain of thesuperfamily of nuclear receptors. Calreticulin binds to antibodiesin certain sera of systemic lupus and Sjogren patients whichcontain anti-Ro/SSA antibodies, it is highly conserved amongspecies, and it is located in the endoplasmic and sarcoplasmic< |
Immunogen | n/a |
Other Names | [Calreticulin; CRP55; Calregulin; Endoplasmic reticulum resident protein 60; ERp60; HACBP; grp60; CALR; CRTC] |
Gene, Accession # | [CALR], Gene ID: 811, NCBI: NP_004334.1, UniProt: P27797 |
Catalog # | MBS9214520 |
Price | $165, $370 |
Order / More Info | CALR Antibody from MYBIOSOURCE INC. |
Product Specific References | Du, X.L., et al. Oncogene 28(42):3714-3722(2009) Sato, H., et al. Biochim. Biophys. Acta 1790(10):1198-1205(2009) Abd Alla, J., et al. Biochem. Biophys. Res. Commun. 387(1):186-190(2009) |