Heat Shock Factor 1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHeat Shock Factor 1
Clonemonoclonal
Host SpeciesRat
Reactive Specieshuman, mouse, rat
IsotypeIgG1k
Formataffinity purified
Size0.1 mg
Concentrationn/a
ApplicationsELISA (EIA), Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC)
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DescriptionThis antibody recognizes GST-fusion proteins. Heat-shock factor 1 (HSF1) is the master transcriptional regulator to respond to the cellular stress signals, such as heat, heavy metals, and oxidative reagents and a wide variety of other stressors. It binds to heat shock response elements (HSEs) in the upstream region of heat shock gene and activates their transcription. Some laboratories have reported that the constitutive, non-DNA binding, monomeric form of inactive HSF1 is located in the cytoplasm. Upon activation, HSF1 is trimerized and is localized in nucleus where it binds DNA. The increased HSF1 which is associated with reduced breast cancer survival may imply that HSF1 should be evaluated prospectively as an independent prognostic indi
ImmunogenAntigen Preparation: A recombinant mouse HSF1 (1-503aa) protein.
Other Names[Rat HSF1; Heat shock factor protein 1; Heat Shock Factor 1 (HSF1); Heat shock transcription factor (HSTF1); Rat HSF1], [HSF1; HSTF1]
Gene, Accession #[HSF1], Gene ID: 3297
Catalog #MBS460642
Price$285
Order / More InfoHeat Shock Factor 1 Antibody from MYBIOSOURCE INC.
Product Specific ReferencesNunes,S.L. and Calderwood,S.K. Heat shock factor-1 and the heat shock cognate 70 protein associate in high molecular weight complexes in the cytoplasm of NIH-3T3 cells. Biochem. Biophys. Res. Commun. 213 (1), 1-6 (1995).
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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