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Antigenic Specificity | CD1a / HTA1 (Mature Langerhans Cells Marker) |
Clone | [CBT6] |
Host Species | Mouse |
Reactive Species | human, mouse |
Isotype | IgG1, kappa |
Format | unconjugated |
Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: At least five CD1 genes (CD1a, b, c, d, and e) are identified. CD1 proteins have been demonstrated to restrict T cell response to non-peptide lipid and glycolipid antigens and play a role in non-classical antigen presentation. CD1a is a non-polymorphic MHC Class 1 related cell surface glycoprotein, expressed in association with Beta-2 microglobulin. Anti-CD1a labels Langerhans cell histiocytosis (Histiocytosis X), extranodal histiocytic sarcoma, a subset of T-lymphoblastic lymphoma/leukemia, and interdigitating dendritic cell sarcoma of the lymph node. When combined with antibodies against TTF-1 and CD5, anti-CD1a is useful in distinguishing between pulmonary and thymic neoplasms since CD1a is consistently expressed in thymic l |
Immunogen | Immunogen: Human CD1a |
Other Names | [Cortical thymocyte antigen CD1A, Epidermal dendritic cell marker CD1a, FCB6, HTA1, T cell surface antigen T6 / Leu 6, T-Cell Surface Glycoprotein CD1A], [CD1A; CD1A; R4; T6; CD1; FCB6; HTA1; hTa1 thymocyte antigen] |
Gene, Accession # | [CD1A], Gene ID: 909, NCBI: NP_001307581.1, UniProt: P06126 |
Catalog # | MBS438742 |
Price | $190, $340, $340 |
Order / More Info | CD1a / HTA1 (Mature Langerhans Cells Marker) Antibody from MYBIOSOURCE INC. |
Product Specific References | van de Rijn M et al. J Immunol 1983, 131(2):851-5 Lerch PG et al. Hum Immunol 1983, 6(1):13-30 Knapp W. et al. (eds) Leukocyte Typing IV, p251-263, Oxford University Press, Oxford, 1989 Khalili-Shirazi A, et al. J Neurol Sci 1998,158(2):154-163. Maher JK and Kronenberg M. Curr Opin Immunol 1997, 9(4):456-461 Blumberg RS et al. Immunol Rev 1995, 147:5-29. Salamone MC et al. Dis Markers 1990, 8(5):275-281 |