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Antigenic Specificity | BSG |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.06 mL, 0.12 mL, 0.2 mL |
Concentration | 1mg/mL |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Basigin (EMMPRIN, CD147) is a type I integral membrane receptor protein belonging to the immunoglobulin superfamily (1). Basigin is a glycosylated protein with four known isoforms, of which isoform 2 is the most abundantly expressed (2). Multiple functions have been ascribed to Basigin; foremost among these is stimulating the secretion of extracellular matrix metalloproteinases by adjacent fibroblasts, a function which has been implicated in promoting tumor progression (2-4). Research studies have shown that Basigin is overexpressed by many tumor cells, and its expression level may correlate with tumor malignancy (5, 6). A recent study identified the BASIGIN gene as a regulatory target of Slug, suggesting a role for Basigin in the process o |
Immunogen | Immunogen: Recombinant protein of human BSG Observed Molecular Weight: 42kDa |
Other Names | [5F7; CD147; EMMPRIN; M6; OK; TCSF] |
Gene, Accession # | [BSG], Gene ID: 682, NCBI: NP_940991.1 |
Catalog # | MBS2516629 |
Price | $150, $225, $360 |
Order / More Info | BSG Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |