Retinoblastoma (pSer780) Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | Retinoblastoma (pSer780) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.05 mL |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rabbit anti retinoblastoma (pSer780) antibody recognizes retinoblastoma gene protein, also known as retinoblastoma-associated protein, p105-Rb, pp110 and Rb, when phosphorylated at serine 780. Retinoblastoma-associated protein is a tumor suppressor protein that plays a key role in G1 checkpoint control. In quiescent cells retinoblastoma-associated protein forms a repressor complex by binding to E2F transcription factors. Phosphorylation of retinoblastoma-associated protein results in dissociation from E2F, allowing for cell cycle progression. Retinoblastoma-associated protein is phosphorylated at serine 780 by cyclin-D-cdk4/6 complexes, p38 MAPK kinase and aurora b kinase (Macdonald and Dick 2012). |
| Immunogen | Immunogen: Phospho specific-peptide corresponding to residues surrounding serine 780 of human retinoblastoma |
| Other Names | [Retinoblastoma (pSer780)], [RB1; RB1; RB; pRb; OSRC; pp110; p105-Rb; PPP1R130; Rb] |
| Gene, Accession # | [RB1], Gene ID: 5925, NCBI: P06400.2, UniProt: P06400 |
| Catalog # | MBS225312 |
| Price | $375 |
| Order / More Info | Retinoblastoma (pSer780) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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