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Antigenic Specificity | TNFRSF1B |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous level of total TNFRSF1B protein. TNF-a is an important cytokine produced by numerous cell types including neutrophils, activated lymphoctyes, macrophages an NK cells. It plays a critical role in inflammatory responses and in apoptosis (1). TNF-a exists as a membrane-anchored and soluble form, both of which show biological activity. Response to TNF-a is mediated through two receptors, TNF-R1, which is widely expressed, and TNF-R2, which is expressed mainly in immune and endothelial cells (2). Antagonists to TNF-a have been validated as therapeutic targets for rheumatoid arthritis and other immune disorders (3). |
Immunogen | Immunogen Type: Recombinant Protein Immunogen Description: Recombinant protein of human TNFRSF1B. |
Other Names | [TNFRSF1B; CD120b; TBPII; TNF-R-II; TNF-R75] |
Gene, Accession # | [TNFRSF1B], Gene ID: 7133, NCBI: NP_001057.1, UniProt: P20333 |
Catalog # | MBS9407062 |
Price | $255 |
Order / More Info | TNFRSF1B Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |