TNFRSF1B Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityTNFRSF1B
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatimmunogen affinity purified
Size0.1 mL
Concentration1.0 mg/ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC)
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DescriptionThe antibody detects endogenous level of total TNFRSF1B protein. TNF-a is an important cytokine produced by numerous cell types including neutrophils, activated lymphoctyes, macrophages an NK cells. It plays a critical role in inflammatory responses and in apoptosis (1). TNF-a exists as a membrane-anchored and soluble form, both of which show biological activity. Response to TNF-a is mediated through two receptors, TNF-R1, which is widely expressed, and TNF-R2, which is expressed mainly in immune and endothelial cells (2). Antagonists to TNF-a have been validated as therapeutic targets for rheumatoid arthritis and other immune disorders (3).
ImmunogenImmunogen Type: Recombinant Protein Immunogen Description: Recombinant protein of human TNFRSF1B.
Other Names[TNFRSF1B; CD120b; TBPII; TNF-R-II; TNF-R75]
Gene, Accession #[TNFRSF1B], Gene ID: 7133, NCBI: NP_001057.1, UniProt: P20333
Catalog #MBS9407062
Price$255
Order / More InfoTNFRSF1B Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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