Mouse Erbb2 (P1236) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Mouse Erbb2 (P1236) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | mouse, rat |
| Isotype | n/a |
| Format | purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.5 |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This Mouse Erbb2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 1236-1268 amino acids from the Mouse Erbb2. Protein tyrosine kinase that is part of several cell surface receptor complexes, but that apparently needs a coreceptor for ligand binding. Essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. GP30 is a potential ligand for this receptor. Regulates outgrowth and stabilization of peripheral microtubules (MTs). Upon ERBB2 activation, the MEMO1-RHOA-DIAPH1 signaling pathway elicits the phosphorylation and thus the inhibition of GSK3B at cell membrane. This prevents the phosphorylation of APC and CLASP2, allowing its association with the ce |
| Immunogen | n/a |
| Other Names | [Receptor tyrosine-protein kinase erbB-2; Proto-oncogene Neu; Proto-oncogene c-ErbB-2; p185erbB2; CD340; Erbb2; Kiaa3023; Neu] |
| Gene, Accession # | [Erbb2], Gene ID: 13866, NCBI: NP_001003817.1, UniProt: P70424 |
| Catalog # | MBS9209362 |
| Price | $165, $370 |
| Order / More Info | Mouse Erbb2 (P1236) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Okazaki N.,et al.DNA Res. 10:167-180(2003). Lim J.,et al.Endocrinology 138:1328-1337(1997). Moscoso L.M.,et al.Dev. Biol. 172:158-169(1995). Muthuswamy S.K.,et al.Oncogene 11:271-279(1995). Jaulin-Bastard F.,et al.J. Biol. Chem. 276:15256-15263(2001). |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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