IRS-2 Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | IRS-2 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, rat, mouse |
| Isotype | n/a |
| Format | epitope affinity purified |
| Size | 0.1 mg |
| Concentration | Size: 100 ug/200 ul |
| Applications | ELISA, Western Blot, Immunohistochemistry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This antibody recognizes ~180 kDa of human IRS-2. It also reacts with mouse and rat. The other species are not tested. Insulin Receptor Substrate-2 (IRS-2), a 180kDa cytoplasmic docking protein, is one of the major endogenous substrates of the insulin receptor kinase. The insulin receptor mediates insulin action through the phosphorylation of substrate proteins. The major substrates of the insulin receptor kinase are the insulin receptor substrate (IRS) family of proteins, IRS 1, IRS 2, IRS 3, and IRS 4. IRS 2, a signaling molecule that mediates effects of insulin, Insulin-like growth factor 1 and other cytokines by acting as a molecular adaptor between diverse receptor kinases and downstream effectors. IRS proteins contain more than 70 pot |
| Immunogen | Antigen Preparation: A synthetic peptide corresponding to the intra domain of IRS-2 protein. It is identical within human, rat and mouse origins. |
| Other Names | [Rabbit IRS-2; Insulin-receptor substrate 2 (IRS-2).], [IRS2; IRS2; IRS-2] |
| Gene, Accession # | [IRS-2], Gene ID: 8660, NCBI: NP_003740.2, UniProt: Q96RG4 |
| Catalog # | MBS462061 |
| Price | $270 |
| Order / More Info | IRS-2 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Li, Y. et al. (2004) J. Biol. Chem. 279, 45304-45307. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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