Edit |   |
---|---|
Antigenic Specificity | TRIF |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, Immunohistochemistry (IHC) Formalin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Rabbit IgG polyclonal antibody for TIR domain-containing adapter molecule 1(TICAM1) detection. Tested with WB, IHC-P, IHC-F in Human. Background: TICAM(TIR DOMAIN-CONTAINING ADAPTOR MOLECULE 1), also known as TICAM1 or TRIF, is an adapter in responding to activation of toll-like receptors(TLRs). It mediates the rather delayed cascade of two TLR-associated signaling cascades, where the other one is dependent upon a MyD88 adapter. By genomic sequence analysis, Oshiumi et al.(2003) mapped the TICAM1 gene to chromosome 19p13.3. By coimmunoprecipitation analysis, Oshiumi et al.(2003) showed that TICAM1 interacts specifically with TLR3, but not with other TLRs. Functional analysis showed that the association of TLR3 and TICAM1 mediat |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human TRIF (692-712aa NNHMWNQRGSQAPEDKTQEAE). |
Other Names | [TIR domain-containing adapter molecule 1; toll-like receptor adaptor molecule 1; HSD34; MGC35334; Proline rich vinculin and TIR domain containing protein B; Proline-rich; PRVTIRB; Putative NF kappa B activating protein 502H; Putative NF-kappa-B-activating protein 502H; Putative NFkB activating protein; Ring finger protein 36; RNF36; TCAM1_HUMAN; TICAM 1; TICAM-1; TICAM1; TIR domain containing adapter molecule 1; TIR domain containing adapter protein inducing IFN beta; TIR domain containing adaptor inducing interferon beta; TIR domain-containing adapter molecule 1; TIR domain-containing adapter protein inducing IFN-beta; Toll interleukin 1 receptor domain containing adapter protein inducing interferon beta; Toll like receptor adaptor molecule 1; Toll-interleukin-1 receptor domain-containing adapter protein inducing interferon beta; TRIF; TRIF protein; TRIM 69; TRIM69; Trimless; Tripartite motif containing 69; vinculin and TIR domain-containing protein B], [TICAM1; TICAM1; TRIF; IIAE6; MyD88-3; PRVTIRB; TICAM-1; PRVTIRB; TRIF; TICAM-1; MyD88-3; TIR domain-containing adapter protein inducing IFN-beta] |
Gene, Accession # | [TICAM1], Gene ID: 148022, NCBI: Q8IUC6.1, UniProt: Q8IUC6 |
Catalog # | MBS176036 |
Price | $315 |
Order / More Info | TRIF Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |