TLK1 Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | TLK1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | immunogen affinity purified |
| Size | 0.05 mL, 0.1 mL |
| Concentration | 1.0 mg/ml |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The antibody detects endogenous levels of total TLK1 protein. Rapidly and transiently inhibited by phosphorylation following the generation of DNA double-stranded breaks during S-phase. This is cell cycle checkpoint and ATM-pathway dependent and appears to regulate processes involved in chromatin assembly. Isoform 3 phosphorylates and enhances the stability of the t-SNARE SNAP23, augmenting its assembly with syntaxin. Isoform 3 protects the cells from the ionizing radiation by facilitating the repair of DSBs. In vitro, phosphorylates histone H3 at 'Ser-10'.Yamakawa A., Gene 202:193-201(1997).Sillje H.H.W., EMBO J. 18:5691-5702(1999).Cabaniols J.-P., Mol. Biol. Cell 10:4033-4041(1999). |
| Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized peptide derived from internal of human TLK1. |
| Other Names | [kinase TLK1; PKU-beta; tousled-like kinase 1] |
| Gene, Accession # | [TLK1], Gene ID: 9874, NCBI: NP_001130026.1, UniProt: Q9UKI8 |
| Catalog # | MBS9401906 |
| Price | $200, $255 |
| Order / More Info | TLK1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
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