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Antigenic Specificity | Eif2ak2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous level of total Eif2ak2 antibody. IFN-induced dsRNA-dependent serine/threonine-protein kinase which plays a key role in the innate immune response to viral infection and is also involved in the regulation of signal transduction, apoptosis, cell proliferation and differentiation. Exerts its antiviral activity on a wide range of DNA and RNA viruses including hepatitis C virus (HCV), hepatitis B virus (HBV), measles virus (MV) and herpes simplex virus 1 (HHV-1). Inhibits viral replication via phosphorylation of the alpha subunit of eukaryotic initiation factor 2 (EIF2S1), this phosphorylation impairs the recycling of EIF2S1 between successive rounds of initiation leading to inhibition of translation which eventua |
Immunogen | Immunogen Type: Recombinant Protein Immunogen Description: Recombinant protein of mouse Eif2ak2. |
Other Names | [Pkr; Tik; Prkr; AI467567; AI747578; 2310047A08Rik; 4732414G15Rik] |
Gene, Accession # | [Eif2ak2], Gene ID: 5610, NCBI: NP_001129123.1, UniProt: P19525 |
Catalog # | MBS9405022 |
Price | $255 |
Order / More Info | Eif2ak2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |