Edit |   |
---|---|
Antigenic Specificity | Phospho-VEGFR2(Tyr1214) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-VEGFR2(Tyr1214) antibody detects endogenous levels of VEGFR2 only when phosphorylated at Tyrosine 1214. Description: VEGFR-2 is a receptor tyrosine kinase of the VEGFR family. High affinity receptor for VEGF and VEGF-C. Ligand binding induces autophosphorylation and activation. Activated receptor recruits proteins including Shc, GRB2, PI3K, Nck, SHP-1 and SHP-2. Plays a key role in vascular development and regulation of vascular permeability.Function: Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFC and VEGFD. Plays an essential role in the regulation of angiogenesis, vascular development, vascular permeability, and embryonic hematopoiesis. Promotes proliferation, survival, migration and |
Immunogen | Immunogen: A synthesized peptide derived from human VEGFR2 around the phosphorylation site of Tyrosine 1214 Subcellular Location: Membrane. Tissue Specificity: Detected in cornea (at protein level). Widely expressed. |
Other Names | [CD309; CD309 antigen; EC 2.7.10.1; Fetal liver kinase 1; FLK-1; FLK1; FLK1, mouse, homolog of; Kdr; Kinase insert domain receptor (a type III receptor tyrosine kinase); Kinase insert domain receptor; KRD1; Ly73; Protein tyrosine kinase receptor FLK1; Protein-tyrosine kinase receptor flk-1; soluble VEGFR2; Tyrosine kinase growth factor receptor; Vascular endothelial growth factor receptor 2; VEGFR 2; VEGFR; VEGFR-2; VEGFR2; VGFR2_HUMAN] |
Gene, Accession # | [VEGFR2], Gene ID: 3791, NCBI: NP_002244.1, UniProt: P35968 |
Catalog # | MBS9600001 |
Price | $240, $280 |
Order / More Info | Phospho-VEGFR2(Tyr1214) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |