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Antigenic Specificity | CD154 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | epitope affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Flow Cytometry (FC/FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody reacts with human. The other species are not tested. CD154 / CD40 ligand (CD40L) is a 33 kDa type II membrane glycoprotein expressed mainly on the cell surface of activated T lymphocytes, but also exists as a soluble form extracellularly. CD40L is the ligand for CD40, a member of the TNF superfamily, which is expressed on the cell surface of B cells, macrophages/monocytes, dendritic cells, vascular endothelial cells, and epithelial cells. CD40L plays an important role in B cell proliferation, antibody class switching, modulation of apoptosis in the germinal center through interaction with B cells expressing CD40, and activation of CD4+ T cells. Mutation within the CD40L gene is linked to hyper IgM syndrome, an X linked immunod |
Immunogen | n/a |
Other Names | n/a |
Gene, Accession # | [CD154], Gene ID: 959 |
Catalog # | MBS460102 |
Price | $285 |
Order / More Info | CD154 Antibody from MYBIOSOURCE INC. |
Product Specific References | Graf, D., Korthauer, U., Mages, H.W., Senger, G. and Kroczek, R.A. Cloning of TRAP, a ligand for CD40 on human T cells. Eur. J. Immunol. 22 (12), 3191-3194 (1992). |