CD154 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCD154
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatepitope affinity purified
Size0.1 mg
Concentrationn/a
ApplicationsELISA (EIA), Flow Cytometry (FC/FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB)
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DescriptionThis antibody reacts with human. The other species are not tested. CD154 / CD40 ligand (CD40L) is a 33 kDa type II membrane glycoprotein expressed mainly on the cell surface of activated T lymphocytes, but also exists as a soluble form extracellularly. CD40L is the ligand for CD40, a member of the TNF superfamily, which is expressed on the cell surface of B cells, macrophages/monocytes, dendritic cells, vascular endothelial cells, and epithelial cells. CD40L plays an important role in B cell proliferation, antibody class switching, modulation of apoptosis in the germinal center through interaction with B cells expressing CD40, and activation of CD4+ T cells. Mutation within the CD40L gene is linked to hyper IgM syndrome, an X linked immunod
Immunogenn/a
Other Namesn/a
Gene, Accession #[CD154], Gene ID: 959
Catalog #MBS460102
Price$285
Order / More InfoCD154 Antibody from MYBIOSOURCE INC.
Product Specific ReferencesGraf, D., Korthauer, U., Mages, H.W., Senger, G. and Kroczek, R.A. Cloning of TRAP, a ligand for CD40 on human T cells. Eur. J. Immunol. 22 (12), 3191-3194 (1992).
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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