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Antigenic Specificity | ch-Alk2 |
Clone | polyclonal |
Host Species | Sheep |
Reactive Species | chicken |
Isotype | n/a |
Format | ammonium sulfate precipitate |
Size | 0.25 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Activin Receptor-Like Kinase 2 is a member of the superfamily of type I receptors for transforming growth factor- (TGF-). This receptor binds both activin and bone morphogenic proteins (BMPs). In mice, these receptors are expressed mainly in the extraembryonic visceral endoderm before gastrulation and later in both embryonic and extraembryonic cells during gastrulation. Also, it has been shown that ALK2 associates with and phosphorylates Smad1 and also regulated Smad5 and Smad8 phosphorylation. Additionally, it induces the Tlx2 promoter in the absense of BMP7. |
Immunogen | Immunogen: Recombinant protein derived from the extracellular domain of the chicken ALK2 protein. Protein shares significant homology with the mouse, rat and human sequences. |
Other Names | [Activin Receptor-Like Kinase 2], [ACVR1; ACVR1] |
Gene, Accession # | [ch-Alk2], Gene ID: 395246, NCBI: NP_989891.1, UniProt: Q90ZK6 |
Catalog # | MBS395823 |
Price | $340 |
Order / More Info | ch-Alk2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |