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Antigenic Specificity | SYP |
Clone | [7H12] |
Host Species | Mouse |
Reactive Species | human, rat |
Isotype | IgG1 |
Format | ascites |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FC/FACS), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Synaptophysin (p38) is an integral membrane protein of small synaptic vesicles in brain and endocrine cells.Synaptophysin contains four transmembrane domains that form a hexameric channel or gap junction-like pore. Synaptophysin binds to the SNARE protein synaptobrevin/VAMP, which prevents the inclusion of synaptobrevin in the synaptic vesicle fusion complex and creates a pool of synaptobrevin for exocytosis when synapse activity increases. Synaptophysin is also responsible for targeting synaptobrevin 2/VAMP2 to synaptic vesicles, a critical component of the fusion complex. |
Immunogen | Immunogen: Purified recombinant fragment of SYP expressed in E. Coli. |
Other Names | [MRXSYP; SYP] |
Gene, Accession # | [SYP], Gene ID: 6855, NCBI: NP_003170.1, UniProt: P08247 |
Catalog # | MBS8538615 |
Price | $280 |
Order / More Info | SYP Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |