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Antigenic Specificity | Hax1a [8F9G7] |
Clone | [8F9G7] |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Hax1a Monoclonal Antibody: The HS-1 associated protein X-1 (Hax1) was initially identified in a yeast two-hybrid assay on the basis of its ability to bind to the hemapoietic cell-specific protein 1 (HS-1). Hax1 possesses anti-apoptotic activity and is structurally related to Bcl-2 family members, including the presence of BH1- and BH2-like domains. It has recently been shown to interact with HIV viral protein R (Vpr), a protein required for viral pathogenesis of HIV and linked to T-cell apoptosis through activation of caspases 3 and 9. Other studies indicate that Hax1-mediated processing of HtrA2 (also known as Omi) by the mitochondrial protease PARL allows survival of lymphocytes and neurons when cytokines are limiting. At least four isofo |
Immunogen | Immunogen: Mouse monoclonal Hax1a antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human Hax1a. Buffer: Hax1a Monoclonal Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [Hax1a [8F9G7] : SCN3; HS1BP1; HCLSBP1; HCLS1 associated protein X-1], [HAX1; HAX1; SCN3; HS1BP1; HCLSBP1; HS1BP1; HAX-1; HSP1BP-1] |
Gene, Accession # | [HAX1], Gene ID: 10456, NCBI: NP_006109, UniProt: O00165 |
Catalog # | MBS150035 |
Price | $375 |
Order / More Info | Hax1a [8F9G7] Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |