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Antigenic Specificity | CIP75 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CIP75 Antibody: The ubiquitin-proteosome pathway of protein degradation is one of the mechanisms that ensure the proper level of cellular proteins. The ubiquitin-like (UbL) and ubiquitin-associated (UBA) domain containing protein family is thought to be involved in proteosomal degradation. One such protein is CIP75, also known as ubiquilin-4, interacts with a number of proteins such as Ataxin-1 and Connexin-43, resulting in an increased rate of turnover of these proteins. Overexpression CIP75 led to a significant reduction of Connexin-43 half-life, with the opposite being observed in siRNA knockdown experiments. CIP75 contains an N-terminal UbL domain which is thought to interact with proteins of the 26S proteosome complex and a C-terminal |
Immunogen | Immunogen: CIP75 antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human CIP75. Buffer: CIP75 Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [CIP75; A1U; A1Up; UBIN; CIP75; C1orf6; Ubiquilin-4; Ataxin-1 interacting ubiquitin-like protein; ubiquilin 4], [UBQLN4; UBQLN4; A1U; A1Up; UBIN; CIP75; C1orf6; C1orf6; CIP75; UBIN; A1Up; CIP75] |
Gene, Accession # | [UBQLN4], Gene ID: 56893, NCBI: Q9NRR5.2, UniProt: Q9NRR5 |
Catalog # | MBS151318 |
Price | $375 |
Order / More Info | CIP75 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |