CIP75 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCIP75
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mg
Concentration1 mg/mL
ApplicationsELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
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DescriptionCIP75 Antibody: The ubiquitin-proteosome pathway of protein degradation is one of the mechanisms that ensure the proper level of cellular proteins. The ubiquitin-like (UbL) and ubiquitin-associated (UBA) domain containing protein family is thought to be involved in proteosomal degradation. One such protein is CIP75, also known as ubiquilin-4, interacts with a number of proteins such as Ataxin-1 and Connexin-43, resulting in an increased rate of turnover of these proteins. Overexpression CIP75 led to a significant reduction of Connexin-43 half-life, with the opposite being observed in siRNA knockdown experiments. CIP75 contains an N-terminal UbL domain which is thought to interact with proteins of the 26S proteosome complex and a C-terminal
ImmunogenImmunogen: CIP75 antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human CIP75. Buffer: CIP75 Antibody is supplied in PBS containing 0.02% sodium azide.
Other Names[CIP75; A1U; A1Up; UBIN; CIP75; C1orf6; Ubiquilin-4; Ataxin-1 interacting ubiquitin-like protein; ubiquilin 4], [UBQLN4; UBQLN4; A1U; A1Up; UBIN; CIP75; C1orf6; C1orf6; CIP75; UBIN; A1Up; CIP75]
Gene, Accession #[UBQLN4], Gene ID: 56893, NCBI: Q9NRR5.2, UniProt: Q9NRR5
Catalog #MBS151318
Price$375
Order / More InfoCIP75 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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