Beta III Tubulin Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityBeta III Tubulin
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatimmunogen affinity purified
Size0.1 mg
Concentrationn/a
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC) Paraffin
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DescriptionRabbit IgG polyclonal antibody for Tubulin beta-3 chain(TUBB3) detection. Background: Tubulin beta-3 chain is a protein that in humans is encoded by the TUBB3 gene. This gene encodes a class III member of the beta tubulin protein family. Beta tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. This protein is primarily expressed in neurons and may be involved in neurogenesis and axon guidance and maintenance. Mutations in this gene are the cause of congenital fibrosis of the extraocular muscles type 3. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 6.
ImmunogenImmunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human Beta III Tubulin (383-412aa EQFTAMFRRKAFLHWYTGEGMDEMEFTEAE), identical to the related mouse and rat sequences.
Other Names[beta 3 tubulin; beta-4; CDCBM; CDCBM1; CFEOM3A; CFEOM3; FEOM3; M(beta)3; M(beta)6; MC1R; Tubb 3; TUBB3; TUBB4; Tubulin beta 3; Tubulin beta 3 chain; Tubulin beta 4; Tubulin beta-4 chain; Tubulin beta III; Tubulin beta-III; Q13509; tubulin beta 3 class III], [TUBB3; TUBB3; CDCBM; FEOM3; TUBB4; CDCBM1; CFEOM3; beta-4; CFEOM3A; TUBB4]
Gene, Accession #[TUBB3], Gene ID: 10381, NCBI: NP_001184110.1, UniProt: Q13509
Catalog #MBS178655
Price$315
Order / More InfoBeta III Tubulin Antibody from MYBIOSOURCE INC.
Product Specific References1. Ranganathan S, Dexter DW, Benetatos CA, Hudes GR (Mar 1998). Cloning and sequencing of human betaIII-tubulin cDNA: induction of betaIII isotype in human prostate carcinoma cells by acute exposure to antimicrotubule agents. Biochim Biophys Acta. 1395 (2): 237-45.2. Cicchillitti L, Penci R, Di Michele M, Filippetti F, Rotilio D, Donati MB, Scambia G, Ferlini C (July 2008).
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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