Phospho- STAT4 (pTyr 693) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Phospho- STAT4 (pTyr 693) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, rat, mouse, dog |
| Isotype | n/a |
| Format | epitope affinity purified |
| Size | 0.1 mg |
| Concentration | Size: 100 ug/200 ul |
| Applications | ELISA, Western Blot, Immunohistochemistry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This antibody recognizes STAT4 (pY693) with a phosphorylated sites of Tyr693. It does not cross-react with non-phosphospecific peptide. STAT proteins (Signal transducer and activator of transcription) belong to a family of cytoplasmic transcription factors that can be phosphorylated by a lignad binding to its cell surface receptor. Activation of STAT4 induces dimerization, nuclear translocation and DNA binding. STAT4 protein expression is restricted to the thymus, spleen and testis. Both tyrosine and serine residues on STAT4 become phosphorylated in response to IL-12 or IFN-alpha although serine phosphorylation is not required for DNA binding. STAT4 is activated in T-cells in response to the cytokine interleukin-12 (IL-12), and in NK cells |
| Immunogen | Antigen Preparation: A synthetic peptide surrounding to the epitope -KGYVP-- with phosphorylation sites at Tyr693 of STAT4 protein from human, mouse, rat, chicken dog and bovine origins. |
| Other Names | [Rabbit Phospho-STAT4 (pY693); Signal transducer and activator of transcription 4 (STAT4)], [STAT4; STAT4; SLEB11] |
| Gene, Accession # | [STAT4 (pY693)], Gene ID: 6775, NCBI: NP_003142.1, UniProt: Q14765 |
| Catalog # | MBS462115 |
| Price | $285 |
| Order / More Info | Phospho- STAT4 (pTyr 693) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Takuya Miyagi, et al. High basal STAT4 balanced by STAT1 induction to control type 1 interferon effects in natural killer cells. J Exp Med. 2007 October 1; 204 (10): 2383-2396. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
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