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Antigenic Specificity | RAP80 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: RAP80 Antibody detects endogenous levels of total RAP80. Ubiquitin-binding protein that specifically recognizes and binds ' Lys-63'-linked ubiquitin. Plays a central role in the BRCA1-A complex by specifically binding ' Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at double-strand breaks (DSBs). |
Immunogen | Immunogen: A synthesized peptide derived from human RAP80 |
Other Names | [BRCA1-A complex subunit RAP80; RAP80; Receptor associated protein 80; RIP110; Rxrip110; UIMC1; X2HRIP110] |
Gene, Accession # | [RAP80], Gene ID: 51720, NCBI: NP_001186226.1, UniProt: Q96RL1 |
Catalog # | MBS4751157 |
Price | $335 |
Order / More Info | RAP80 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |