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Antigenic Specificity | DFF40 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | DFF40 Antibody: Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain containing adapter molecules and members of the caspase family of proteases. These death signals finally cause the degradation of chromosomal DNA by activated DNase. A mouse DNase that causes DNA fragmentation was identified recently and designated CAD for caspase activated deoxyribonuclease. The human homologue of mouse CAD was more recently identified by three groups independently and termed CPAN, DFF40, and human CAD, respectively. DFF45/ICAD is the inhibitory protein of DFF40/CAD and forms complex with DFF40/CAD. Upon cleavage of DFF45/ICAD by activated caspase, DFF40/ |
Immunogen | Immunogen: DFF40 antibody was raised against a 16 amino acid peptide near the amino terminus of human DFF40. Buffer: DFF40 Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [DFF40; CAD; CPAN; 40kDa; DFF40; Didff; 5730477D02Rik; Cad; DNA fragmentation factor subunit beta; Caspase-activated deoxyribonuclease; CAD; DNA fragmentation factor, beta subunit], [Dffb; Dffb; CAD; CPAN; 40kDa; DFF40; Didff; 5730477D02Rik; Cad; CAD; Caspase-activated DNase; DFF-40] |
Gene, Accession # | [Dffb], Gene ID: 13368, NCBI: NP_031885, UniProt: O54788 |
Catalog # | MBS150231 |
Price | $375 |
Order / More Info | DFF40 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |