Edit |   |
---|---|
Antigenic Specificity | PAK2 (N-term), 192-222 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 1.8 |
Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This PAK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 192-222 amino acids from the N-terminal region of human PAK2. PAK2, a member of the STE20 subfamily of Ser/Thr protein kinases, acts on a variety of targets. It phosphorylates ribosomal protein S6, histone H4 and myelin basic protein. PAK2 interacts tightly with GTP-bound but not GDP-bound CDC42/p21 and RAC1. Expression is ubiquitous, with higher levels seen in skeletal muscle, ovary, thymus and spleen. PAK2 is autophosphorylated when activated by CDC42/p21. The protein structure contains 1 CRIB domain. |
Immunogen | n/a |
Other Names | [Serine/threonine-protein kinase PAK 2; Gamma-PAK; PAK65; S6/H4 kinase; p21-activated kinase 2; PAK-2; p58; PAK-2p27; p27; PAK-2p34; p34; C-t-PAK2; PAK2] |
Gene, Accession # | [PAK2], Gene ID: 5062, NCBI: NP_002568.2, UniProt: Q13177 |
Catalog # | MBS9206557 |
Price | $165, $370 |
Order / More Info | PAK2 (N-term), 192-222 Antibody from MYBIOSOURCE INC. |
Product Specific References | Benner, G.E., et al., J. Biol. Chem. 270(36):21121-21128 (1995). Martin, G.A., et al., EMBO J. 14(9):1970-1978 (1995). Martin, G.A., et al., EMBO J. 14 (17), 4385 (1995). |