ASF1B Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | ASF1B |
| Clone | [AT1D4] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG2b,k |
| Format | Protein A purified |
| Size | 0.05 mL, 0.1 mL |
| Concentration | 1mg/ml |
| Applications | ELISA (EIA), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | ASF1B is a member of the H3/H4 family of histone chaperone proteins and is similar to the anti-silencing function-1 gene in yeast. The encoded protein is the substrate of the tousled-like kinase family of cell cycle-regulated kinases, and may play a key role in modulating the nucleosome structure of chromatin by ensuring a constant supply of histones at sites of nucleosome assembly. Delivering histone H3/H4 dimers to CAF-1 or HIRA histone deposition complexes to facilitate replication-coupled and replication-independent nucleosome assembly on DNA. Both ASF1A and ASF1B are phosphorylated in S phase by the Tousled-like kinases TLK1 and TLK2, and are dephosphorylated when TLK1 and TLK2 are inactivated by Chk1 kinase in response to replicative |
| Immunogen | Immunogen: Recombinant human ASF1B (1-202aa) purified from E. coli |
| Other Names | [ASF1 silencing function 1 homolog B (S.cerevisiae); CIA-II], [ASF1B; ASF1B; CIA-II; hAsf1; hAsf1b; CIA-II; hCIA-II] |
| Gene, Accession # | [ASF1B], Gene ID: 55723, NCBI: NP_060624, UniProt: Q9NVP2 |
| Catalog # | MBS200292 |
| Price | $240, $315 |
| Order / More Info | ASF1B Antibody from MYBIOSOURCE INC. |
| Product Specific References | Corpet A., et al. (2011) EMBO J 30:480-493; Mousson F., et al. (2007) Chromosoma 116:79-93; Hayashi R., et al. (2007) DNA Cell Biol 126:91-99 |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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