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Antigenic Specificity | MSK1 (Ab-212) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total MSK1 protein. Serine/threonine-protein kinase that is required for the mitogen or stress-induced phosphorylation of the transcription factors CREB1 and ATF1 and for the regulation of the transcription factors RELA, STAT3 and ETV1/ER81, and that contributes to gene activation by histone phosphorylation and functions in the regulation of inflammatory genes. Phosphorylates CREB1 and ATF1 in response to mitogenic or stress stimuli such as UV-C irradiation, epidermal growth factor (EGF) and anisomycin. Plays an essential role in the control of RELA transcriptional activity in response to TNF and upon glucocorticoid, associates in the cytoplasm with the glucocorticoid receptor NR3C1 and contributes |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized peptide derived from Internal of human MSK1. |
Other Names | [EC 2.7.11.1; Nuclear mitogen-and stress-activated protein kinase 1; 90 kDa ribosomal protein S6 kinase 5; RSK-like protein kinase; RSKL] |
Gene, Accession # | [MSK1], Gene ID: 9252, NCBI: NP_004746.2, UniProt: O75582 |
Catalog # | MBS9400997 |
Price | $200, $255 |
Order / More Info | MSK1 (Ab-212) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |