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Antigenic Specificity | PABPC4 - middle region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Poly(A)-binding proteins (PABPs) bind to the poly(A) tail present at the 3-prime ends of most eukaryotic mRNAs. PABPC4 or IPABP (inducible PABP) was isolated as an activation-induced T-cell mRNA encoding a protein. Activation of T cells increased PABPC4 mRNA levels in T cells approximately 5-fold. PABPC4 contains 4 RNA-binding domains and proline-rich C terminus. PABPC4 is localized primarily to the cytoplasm. It is suggested that PABPC4 might be necessary for regulation of stability of labile mRNA species in activated T cells. PABPC4 was also identified as an antigen, APP1 (activated-platelet protein-1), expressed on thrombin-activated rabbit platelets. PABPC4 may also be involved in the regulation of protein translation in platelets and m |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PABPC4 |
Other Names | [polyadenylate-binding protein 4 isoform 1; Polyadenylate-binding protein 4; polyadenylate-binding protein 4; poly(A) binding protein cytoplasmic 4; Activated-platelet protein 1; APP-1; Inducible poly(A)-binding protein; iPABP] |
Gene, Accession # | [PABPC4], Gene ID: 8761, NCBI: NP_001129125.1, UniProt: Q13310 |
Catalog # | MBS3219794 |
Price | $335 |
Order / More Info | PABPC4 - middle region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |