PABPC4 - middle region Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPABPC4 - middle region
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formataffinity purified
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionPoly(A)-binding proteins (PABPs) bind to the poly(A) tail present at the 3-prime ends of most eukaryotic mRNAs. PABPC4 or IPABP (inducible PABP) was isolated as an activation-induced T-cell mRNA encoding a protein. Activation of T cells increased PABPC4 mRNA levels in T cells approximately 5-fold. PABPC4 contains 4 RNA-binding domains and proline-rich C terminus. PABPC4 is localized primarily to the cytoplasm. It is suggested that PABPC4 might be necessary for regulation of stability of labile mRNA species in activated T cells. PABPC4 was also identified as an antigen, APP1 (activated-platelet protein-1), expressed on thrombin-activated rabbit platelets. PABPC4 may also be involved in the regulation of protein translation in platelets and m
ImmunogenImmunogen: The immunogen is a synthetic peptide directed towards the middle region of human PABPC4
Other Names[polyadenylate-binding protein 4 isoform 1; Polyadenylate-binding protein 4; polyadenylate-binding protein 4; poly(A) binding protein cytoplasmic 4; Activated-platelet protein 1; APP-1; Inducible poly(A)-binding protein; iPABP]
Gene, Accession #[PABPC4], Gene ID: 8761, NCBI: NP_001129125.1, UniProt: Q13310
Catalog #MBS3219794
Price$335
Order / More InfoPABPC4 - middle region Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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