Edit |   |
---|---|
Antigenic Specificity | FRS3 - middle region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | cow, dog, guinea pig, horse, human, mouse, porcine, rabbit, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This is a rabbit polyclonal antibody against FRS3. It was validated on Western Blot using a cell lysate as a positive control.Target Description: FRS3 is an adapter protein that links FGR and NGF receptors to downstream signaling pathways. FRS3 is involved in the activation of MAP kinases. FRS3 down-regulates ERK2 signaling by interfering with the phosphorylation and nuclear translocation of ERK2.The protein encoded by this gene is a substrate for the fibroblast growth factor receptor. It is found in peripheral plasma membrane and functions in linking FGF receptor stimulation to activators of Ras. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene r |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human FRS3 |
Other Names | [fibroblast growth factor receptor substrate 3; Fibroblast growth factor receptor substrate 3; fibroblast growth factor receptor substrate 3; fibroblast growth factor receptor substrate 3; FGFR-signaling adaptor SNT2; Suc1-associated neurotrophic factor target 2] |
Gene, Accession # | [FRS3], Gene ID: 10817, NCBI: NP_006644, UniProt: O43559 |
Catalog # | MBS3210677 |
Price | $335 |
Order / More Info | FRS3 - middle region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |