Edit |   |
Antigenic Specificity | Thrombin Receptor |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Thrombin Receptor antibody detects endogenous levels of total Thrombin Receptor. Description: PAR1 a G-protein coupled high-affinity receptor for activated thrombin or trypsin. Coupled to G proteins that stimulate phosphoinositide hydrolysis. Coupled to G proteins that stimulate phosphoinositide hydrolysis. May play a role in platelet activation and in vascular development.Function: High affinity receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis. May play a role in platelets activation and in vascular development.Post-translational Modifications: A proteolytic cleavage generates a new N-terminus that functions as a tethered ligand. Phosphorylated in the C-terminal tail; pro |
Immunogen | Immunogen: A synthesized peptide derived from human Thrombin Receptor Subcellular Location: Cell Membrane Tissue Specificity: Platelets and vascular endothelial cells. |
Other Names | [CF2R; Coagulation factor II (thrombin) receptor; Coagulation factor II receptor; F2R; HTR; PAR 1; PAR-1; PAR1; PAR1_HUMAN; Protease activated receptor 1; Proteinase activated receptor 1; Proteinase-activated receptor 1; Thrombin receptor] |
Gene, Accession # | [TR], Gene ID: 2149, NCBI: NP_001298242.1, UniProt: P25116 |
Catalog # | MBS9600200 |
Price | $240, $280 |
Order / More Info | Thrombin Receptor Antibody from MYBIOSOURCE INC. |
Product Specific References | Zhao Y, Zheng Y, Liu X, Luo Q, Wu D, Liu X, Zou L; Journal: Mol Hum Reprod. Inhibiting trophoblast PAR-1 overexpression suppresses sFlt-1-induced anti-angiogenesis and abnormal vascular remodeling: a possible therapeutic approach for preeclampsia. Zhong W, Chen S, Zhang Q, Xiao T, Qin Y, Gu J, Sun B, Liu Y, Jing X, Hu X, Zhang P, Zhou H, Sun T, Yang C; Journal: Oncotarget. Doxycycline directly targets PAR1 to suppress tumor progression. |