Thrombin Receptor Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityThrombin Receptor
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA)
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DescriptionSpecificity: Thrombin Receptor antibody detects endogenous levels of total Thrombin Receptor. Description: PAR1 a G-protein coupled high-affinity receptor for activated thrombin or trypsin. Coupled to G proteins that stimulate phosphoinositide hydrolysis. Coupled to G proteins that stimulate phosphoinositide hydrolysis. May play a role in platelet activation and in vascular development.Function: High affinity receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis. May play a role in platelets activation and in vascular development.Post-translational Modifications: A proteolytic cleavage generates a new N-terminus that functions as a tethered ligand. Phosphorylated in the C-terminal tail; pro
ImmunogenImmunogen: A synthesized peptide derived from human Thrombin Receptor Subcellular Location: Cell Membrane Tissue Specificity: Platelets and vascular endothelial cells.
Other Names[CF2R; Coagulation factor II (thrombin) receptor; Coagulation factor II receptor; F2R; HTR; PAR 1; PAR-1; PAR1; PAR1_HUMAN; Protease activated receptor 1; Proteinase activated receptor 1; Proteinase-activated receptor 1; Thrombin receptor]
Gene, Accession #[TR], Gene ID: 2149, NCBI: NP_001298242.1, UniProt: P25116
Catalog #MBS9600200
Price$240, $280
Order / More InfoThrombin Receptor Antibody from MYBIOSOURCE INC.
Product Specific ReferencesZhao Y, Zheng Y, Liu X, Luo Q, Wu D, Liu X, Zou L; Journal: Mol Hum Reprod. Inhibiting trophoblast PAR-1 overexpression suppresses sFlt-1-induced anti-angiogenesis and abnormal vascular remodeling: a possible therapeutic approach for preeclampsia. Zhong W, Chen S, Zhang Q, Xiao T, Qin Y, Gu J, Sun B, Liu Y, Jing X, Hu X, Zhang P, Zhou H, Sun T, Yang C; Journal: Oncotarget. Doxycycline directly targets PAR1 to suppress tumor progression.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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