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Antigenic Specificity | AKTIP - middle region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | cow, dog, guinea pig, horse, human, mouse, rabbit, rat, zebrafish |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This is a rabbit polyclonal antibody against AKTIP. It was validated on Western Blot using a cell lysate as a positive control.Target Description: AKTIP is the component of the FTS/Hook/FHIP complex (FHF complex). The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting complex (the HOPS complex). AKTIP regulates apoptosis by enhancing phosphorylation and activation of AKT1. AKTIP increases release of TNFSF6 via the AKT1/GSK3B/NFATC1 signaling cascade.The mouse homolog of this gene produces fused toes and thymic hyperplasia in heterozygous mutant animals while homozygous mutants die in early development. This gene may play a role in apoptosis as these morphological abnorma |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human AKTIP |
Other Names | [AKT-interacting protein isoform 1; AKT-interacting protein; AKT-interacting protein; AKT interacting protein; Ft1; Fused toes protein homolog] |
Gene, Accession # | [AKTIP], Gene ID: 64400, NCBI: NP_001012398, UniProt: Q9H8T0 |
Catalog # | MBS3212625 |
Price | $335 |
Order / More Info | AKTIP - middle region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |