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Antigenic Specificity | ZNF76 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.1 mL |
Concentration | 0.2mg/ml |
Applications | Immunohistochemistry (IHC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total ZNF76 protein. ZNF76, also known as ZNF523 or Zfp523, is a transcriptional repressor expressed in the testis. It is the human homolog of the Xenopus Staf protein (selenocysteine tRNA gene transcription-activating factor) known to regulate the genes encoding small nuclear RNA and selenocysteine tRNA. ZNF76 localizes to the nucleus and exerts an inhibitory function on p53-mediated transactivation. ZNF76 specifically targets TFIID (TATA-binding protein). The interaction with TFIID occurs through both its N and C termini. The transcriptional repression activity of ZNF76 is predominantly regulated by lysine modifications, acetylation and sumoylation. ZNF76 is sumoylated by PIAS 1 and is acetylated |
Immunogen | Immunogen: Synthetic peptide of human ZNF76 Immunogen Type: Peptide |
Other Names | [ZNF523; Zfp523; D6S229E] |
Gene, Accession # | [ZNF76], Gene ID: 7629, NCBI: NP_001278961.1, UniProt: P36508 |
Catalog # | MBS9417208 |
Price | $255 |
Order / More Info | ZNF76 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |